Transcription Factor
| Accessions: | 1hjc_D (3D-footprint 20231221) |
| Names: | Acute myeloid leukemia 1 protein, CBF-alpha-2, Core-binding factor subunit alpha-2, Oncogene AML-1, PEA2-alpha B, PEBP2-alpha B, Polyomavirus enhancer-binding protein 2 alpha B subunit, RUNT-RELATED TRANSCRIPTION FACTOR 1, RUNX1_MOUSE, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit |
| Organisms: | Mus musculus |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q03347 |
| Length: | 118 |
| Pfam Domains: | 1-118 Runt domain |
| Sequence: (in bold interface residues) | 1 GELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRN 60 61 ATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPR |
| Interface Residues: | 21, 83, 111, 112, 115, 118 |
| 3D-footprint Homologues: | 6vg8_D, 3wts_A, 6vgd_D, 4l0y_A, 4l18_E |
| Binding Motifs: | 1hjc_D CaaCCACA |
| Binding Sites: | 1hjc_E 1hjc_F |
| Publications: | Tahirov T.H, Inoue-Bungo T, Morii H, Fujikawa A, Sasaki M, Kimura K, Shiina M, Sato K, Kumasaka T, Yamamoto M, Ishii S, Ogata K. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Cell 104:755-67 (2001). [Pubmed] |
| Related annotations: | PaperBLAST |
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