Transcription Factor
Accessions: | 6e8c_A (3D-footprint 20231221) |
Names: | Double homeobox protein 10, Double homeobox protein 4, DUX4_HUMAN |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q9UBX2 |
Length: | 134 |
Pfam Domains: | 5-58 Homeobox domain 25-57 Homeobox KN domain 79-133 Homeobox domain 102-132 Homeobox KN domain |
Sequence: (in bold interface residues) | 1 RGRGRRRRLVWTPSQSEALRAFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLR 60 61 QHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPES 120 121 RIQIWFQNRRARHP |
Interface Residues: | 5, 8, 33, 45, 46, 48, 49, 52, 53, 56, 57, 67, 73, 79, 80, 81, 82, 120, 121, 123, 124, 127, 128, 131, 132 |
3D-footprint Homologues: | 3d1n_M, 5zfz_A, 1au7_A, 1qpi_A, 4xrm_B, 8g87_X, 3l1p_A, 6m3d_C, 3a01_E, 1puf_A, 6a8r_A, 3cmy_A, 2h1k_B, 1fjl_B, 1ig7_A, 3lnq_A, 1jgg_B, 2lkx_A, 1nk2_P, 1zq3_P, 2ld5_A, 7q3o_C, 5jlw_D, 3rkq_B, 1puf_B, 6es3_K, 4xrs_G, 2hdd_A, 4cyc_A, 2r5y_A, 5flv_I, 2hos_A, 1b72_A, 5zjt_E, 7psx_B, 5hod_A, 1e3o_C, 1le8_A, 1du0_A, 4qtr_D |
Binding Motifs: | 6e8c_A TTGATnAnATTAC |
Binding Sites: | 6e8c_B 6e8c_C |
Publications: | Lee JK, Bosnakovski D, Toso EA, Dinh T, Banerjee S, Bohl TE, Shi K, Orellana K, Kyba M, Aihara H. Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA. Cell Rep 25:2955-2962 (2018). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.