DNA Binding Motif

						

			
Accessions: 6e8c_A (3D-footprint 20231221)

			
Names: Double homeobox protein 4
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the double homeodomain of DUX4 in complex with DNA
Length: 13
Consensus: TTGATnAnATTAC
Weblogo: 
PSSM: P0      A      C      G      T
01      6      8      6     76      T
02      0      0      0     96      T
03      0      0     96      0      G
04     96      0      0      0      A
05      6      6      8     76      T
06     24     24     24     24      n
07     76      6      6      8      A
08     24     24     24     24      n
09     96      0      0      0      A
10      0      0      0     96      T
11      0      0      0     96      T
12     76      6      8      6      A
13      6     83      6      1      C
Binding TFs: 6e8c_A (Homeobox domain, Homeobox KN domain)
Binding Sites: 6e8c_B
6e8c_C
			
Publications: Lee JK, Bosnakovski D, Toso EA, Dinh T, Banerjee S, Bohl TE, Shi K, Orellana K, Kyba M, Aihara H. Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA. Cell Rep 25:2955-2962 (2018). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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