Transcription Factor

						

			
Accessions: 2bjc_A (3D-footprint 20231221), 2bjc_B (3D-footprint 20231221)

			
Names: LACI_ECOLI, LACTOSE OPERON REPRESSOR
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P03023
Length: 62
Pfam Domains:      5-50 Bacterial regulatory proteins, lacI family
Sequence: 
(in bold interface residues)		   1 MKPVTLYDVAEYAGVSVATVSRVVNQASHVSAKTREKVEAAMAELNYIPNRCAQQLAGKQ   60
  61 SL
Interface Residues: 6, 7, 16, 17, 18, 19, 21, 22, 28, 29, 30, 53, 56, 57
3D-footprint Homologues: 7ce1_D, 1efa_B, 3oqm_C, 1l1m_B, 5ui5_I, 1zvv_A, 1jft_A, 4i2o_B
Binding Motifs: 2bjc_AB GTAAGCGCTTAC
2bjc_B CGCTTAC
Binding Sites: 2bjc_C / 2bjc_D
			
Publications: Kopke Salinas R, Folkers G.E, Bonvin A.M, Das D, Boelens R, Kaptein R. Altered specificity in DNA binding by the lac repressor: a mutant lac headpiece that mimics the gal repressor. Chembiochem : a European journal of chemical biology 6:1628-37 (2005). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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