DNA Binding Motif

						

			
Accessions: 2bjc_AB (3D-footprint 20231221)

			
Names: LACTOSE OPERON REPRESSOR
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: NMR structure of a protein-DNA complex of an altered specificity mutant of the lac repressor headpiece that mimics the gal repressor
Length: 12
Consensus: GTAAGCGCTTAC
Weblogo: 
PSSM: P0      A      C      G      T
01      5      5     81      5      G
02      6      5      5     80      T
03     80      5      6      5      A
04     96      0      0      0      A
05      0      0     96      0      G
06      0     96      0      0      C
07      0      0     96      0      G
08      0     96      0      0      C
09      0      0      0     96      T
10      5      5      6     80      T
11     80      5      6      5      A
12      5     80      6      5      C
Binding TFs: 2bjc_A / 2bjc_B (Bacterial regulatory proteins, lacI family)
Binding Sites: 2bjc_C / 2bjc_D
			
Publications: Kopke Salinas R, Folkers G.E, Bonvin A.M, Das D, Boelens R, Kaptein R. Altered specificity in DNA binding by the lac repressor: a mutant lac headpiece that mimics the gal repressor. Chembiochem : a European journal of chemical biology 6:1628-37 (2005). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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