Transcription Factor

						

			
Accessions: 1jfs_A (3D-footprint 20231221)

			
Names: HTH-type transcriptional repressor PurR, Pur regulon repressor, PURINE NUCLEOTIDE SYNTHESIS REPRESSOR, PURR_ECOLI
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0ACP7
Length: 339
Pfam Domains:      2-47 Bacterial regulatory proteins, lacI family
   59-324 Periplasmic binding proteins and sugar binding domain of LacI family
   61-307 Periplasmic binding protein domain
  170-330 Periplasmic binding protein-like domain
Sequence: 
(in bold interface residues)		   1 ATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKS   60
  61 IGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLV  120
 121 MCSEYPEPLLAMLEEYRHIPMVVMDFGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREI  180
 181 GVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPT  240
 241 AVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETA  300
 301 FNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYR
Interface Residues: 3, 4, 13, 14, 15, 16, 18, 19, 25, 26, 27, 50, 53, 54
3D-footprint Homologues: 3oqm_C, 7ce1_D, 1efa_B, 1l1m_B, 1jft_A, 1zvv_A
Binding Motifs: 1jfs_A CGcanACg
Binding Sites: 1jfs_B
			
Publications: Huffman J.L, Lu F, Zalkin H, Brennan R.G. Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. Biochemistry 41:511-20 (2002). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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