Transcription Factor

Accessions: 3mlp_E (3D-footprint 20231221)
Names: COE1_MOUSE, Early B-cell factor, O/E-1, OE-1, Transcription factor COE1
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q07802
Length: 303
Pfam Domains: 220-302 IPT/TIG domain
Sequence:
(in bold interface residues)
1 VLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEK 60
61 EKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLL 120
121 THEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVV 180
181 STTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEAATPCIKAISPSEGWTTGGATVII 240
241 IGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRF 300
301 IYT
Interface Residues: 28, 30, 31, 128, 137, 167, 169, 201, 202, 203, 204
3D-footprint Homologues: 3mln_A, 3mlp_F
Binding Motifs: 3mlp_EF TtCCCATGGGAAnAA
Publications: Treiber N, Treiber T, Zocher G, Grosschedl R. Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins. Genes & development 24:2270-5 (2010). [Pubmed]
Related annotations: PaperBLAST

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