DNA Binding Motif

Accessions: 3mlp_EF (3D-footprint 20231221)
Names: Transcription factor COE1
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Early B-cell Factor 1 (Ebf1) bound to DNA
Length: 15
Consensus: TtCCCATGGGAAnAA
Weblogo:
PSSM: P0 A C G T
01 0 4 0 92 T
02 12 12 8 64 t
03 0 96 0 0 C
04 0 96 0 0 C
05 0 96 0 0 C
06 96 0 0 0 A
07 0 0 0 96 T
08 0 0 96 0 G
09 0 0 96 0 G
10 0 0 96 0 G
11 72 8 8 8 A
12 72 8 8 8 A
13 24 24 24 24 n
14 68 12 8 8 A
15 80 8 4 4 A
Type: Heterodimer
Binding TFs: 3mlp_E (IPT/TIG domain)
3mlp_F (IPT/TIG domain)
Binding Sites: 3mlp_G / 3mlp_H
Publications: Treiber N, Treiber T, Zocher G, Grosschedl R. Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins. Genes & development 24:2270-5 (2010). [Pubmed]

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