Transcription Factor

						

			
Accessions: 3q3d_A (3D-footprint 20231221)

			
Names: BMRR_BACSU, Multidrug-efflux transporter 1 regulator
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P39075
Length: 276
Pfam Domains:      5-72 MerR HTH family regulatory protein
     6-44 MerR family regulatory protein
  123-275 GyrI-like small molecule binding domain
Sequence: 
(in bold interface residues)		   1 KESYYSIGEVSKLANVSIKALRYYDKIDLFKPAYVDPDTSYRYYTDSQLIHLDLIKSLKY   60
  61 IGTPLEEMKKAQDLEMEELFAFYTEQERQIREKLDFLSALEQTISLVKKRMKRQMEYPAL  120
 121 GEVFVLDEEEIRIIQTEAEGLGPENVLNASYSKLKKFIESADGFTNNSYGATFSFQPYTS  180
 181 IDEMTYRHIFTPVLTNKQISSITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIA  240
 241 DRQLTVVSDVYELIIPIHYSPKKQEEYRVEMKIRIL
Interface Residues: 19, 22, 23, 26, 39, 41, 42
3D-footprint Homologues: 6xh7_H, 1r8e_A, 5d8c_A, 6xl5_H, 2vz4_A, 6jgx_B, 7ckq_G, 2zhg_A, 6ldi_G, 1r8d_B, 7tea_B, 4r24_B
Binding Motifs: 3q3d_A CCCT
Binding Sites: 3q3d_B
			
Publications: Bachas S, Eginton C, Gunio D, Wade H. Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proceedings of the National Academy of Sciences of the United States of America 108:11046-51 (2011). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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