Transcription Factor
Accessions: | 3q3d_A (3D-footprint 20231221) |
Names: | BMRR_BACSU, Multidrug-efflux transporter 1 regulator |
Organisms: | Bacillus subtilis, strain 168 |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P39075 |
Length: | 276 |
Pfam Domains: | 5-72 MerR HTH family regulatory protein 6-44 MerR family regulatory protein 123-275 GyrI-like small molecule binding domain |
Sequence: (in bold interface residues) | 1 KESYYSIGEVSKLANVSIKALRYYDKIDLFKPAYVDPDTSYRYYTDSQLIHLDLIKSLKY 60 61 IGTPLEEMKKAQDLEMEELFAFYTEQERQIREKLDFLSALEQTISLVKKRMKRQMEYPAL 120 121 GEVFVLDEEEIRIIQTEAEGLGPENVLNASYSKLKKFIESADGFTNNSYGATFSFQPYTS 180 181 IDEMTYRHIFTPVLTNKQISSITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIA 240 241 DRQLTVVSDVYELIIPIHYSPKKQEEYRVEMKIRIL |
Interface Residues: | 19, 22, 23, 26, 39, 41, 42 |
3D-footprint Homologues: | 5d8c_A, 6xl5_H, 2vz4_A, 6jgx_B, 7ckq_G, 2zhg_A, 6ldi_G, 1r8d_B, 7tea_B, 4r24_B, 6xh7_H, 1r8e_A |
Binding Motifs: | 3q3d_A CCCT |
Binding Sites: | 3q3d_B |
Publications: | Bachas S, Eginton C, Gunio D, Wade H. Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proceedings of the National Academy of Sciences of the United States of America 108:11046-51 (2011). [Pubmed] |
Related annotations: | PaperBLAST |
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