Transcription Factor

Accessions: 3q3d_A (3D-footprint 20231221)
Names: BMRR_BACSU, Multidrug-efflux transporter 1 regulator
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P39075
Length: 276
Pfam Domains: 5-72 MerR HTH family regulatory protein
6-44 MerR family regulatory protein
123-275 GyrI-like small molecule binding domain
Sequence:
(in bold interface residues)
1 KESYYSIGEVSKLANVSIKALRYYDKIDLFKPAYVDPDTSYRYYTDSQLIHLDLIKSLKY 60
61 IGTPLEEMKKAQDLEMEELFAFYTEQERQIREKLDFLSALEQTISLVKKRMKRQMEYPAL 120
121 GEVFVLDEEEIRIIQTEAEGLGPENVLNASYSKLKKFIESADGFTNNSYGATFSFQPYTS 180
181 IDEMTYRHIFTPVLTNKQISSITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIA 240
241 DRQLTVVSDVYELIIPIHYSPKKQEEYRVEMKIRIL
Interface Residues: 19, 22, 23, 26, 39, 41, 42
3D-footprint Homologues: 5d8c_A, 6xl5_H, 2vz4_A, 6jgx_B, 7ckq_G, 2zhg_A, 6ldi_G, 1r8d_B, 7tea_B, 4r24_B, 6xh7_H, 1r8e_A
Binding Motifs: 3q3d_A CCCT
Binding Sites: 3q3d_B
Publications: Bachas S, Eginton C, Gunio D, Wade H. Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proceedings of the National Academy of Sciences of the United States of America 108:11046-51 (2011). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.