DNA Binding Site
| Accessions: | 3d70_B (3D-footprint 20231221), 3d71_M (3D-footprint 20231221), 3q3d_B (3D-footprint 20231221) |
| Organisms: | Bacillus subtilis, strain 168 |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Length: | 23 |
| Sequence: | GACCCTCCCCTTAGGGGAGGGTC |
| Type: | Heterodimer |
| Binding TFs: | 3d70_A (MerR family regulatory protein, GyrI-like small molecule binding domain, MerR HTH family regulatory protein) 3d71_A (MerR family regulatory protein, GyrI-like small molecule binding domain, MerR HTH family regulatory protein) 3q3d_A (MerR family regulatory protein, GyrI-like small molecule binding domain, MerR HTH family regulatory protein) |
| Binding Motifs: | 3d70_A CccT 3d71_A CCCT 3q3d_A CCCT |
| Publications: | Newberry K.J, Huffman J.L, Miller M.C, Vazquez-Laslop N, Neyfakh A.A, Brennan R.G. Structures of BmrR-drug complexes reveal a rigid multidrug binding pocket and transcription activation through tyrosine expulsion. The Journal of biological chemistry 283:26795-804 (2008). [Pubmed] Bachas S, Eginton C, Gunio D, Wade H. Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proceedings of the National Academy of Sciences of the United States of America 108:11046-51 (2011). [Pubmed] |
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