Transcription Factor

Accessions: 5hlh_F (3D-footprint 20231221), 5hlh_H (3D-footprint 20231221)
Names: MarR family transcriptional regulator, Q5HKZ1_STAEQ
Organisms: Staphylococcus epidermidis, strain ATCC 35984 / RP62A
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q5HKZ1
Length: 136
Pfam Domains: 30-87 Sugar-specific transcriptional regulator TrmB
34-92 MarR family
35-101 Winged helix DNA-binding domain
35-92 MarR family
40-108 HxlR-like helix-turn-helix
48-89 FeoC like transcriptional regulator
58-104 Transcriptional regulator PadR-like family
Sequence:
(in bold interface residues)
1 MKQEQMRLANQLFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRH 60
61 LDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDET 120
121 KYVFEELEQTLKHLIE
Interface Residues: 55, 64, 65, 66, 67, 69, 70, 71, 73, 74, 91
3D-footprint Homologues: 7el3_B, 3q5f_A, 6jbx_A, 4lln_I, 7dvv_A, 5yi2_J, 5h3r_A, 1z9c_A, 6c2s_C, 5hlg_E, 3zpl_B, 5f7q_C, 4aik_A, 4fx4_B, 5hso_A
Binding Motifs: 5hlh_FH CGATTnAGnnnnCTnAATCG
Binding Sites: 5hlh_M / 5hlh_N
Publications: Liu G, Liu X, Xu H, Liu X, Zhou H, Huang Z, Gan J, Chen H, Lan L, Yang CG. Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J Am Chem Soc 139:1598-1608 (2017). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.