DNA Binding Motif

						

			
Accessions: 5hlh_FH (3D-footprint 20231221)

			
Names: MarR family transcriptional regulator
Organisms: Staphylococcus epidermidis, strain ATCC 35984 / RP62A
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the overoxidized AbfR bound to DNA
Length: 20
Consensus: CGATTnAGnnnnCTnAATCG
Weblogo: 
PSSM: P0      A      C      G      T
01      0     96      0      0      C
02      0      0     96      0      G
03     90      2      2      2      A
04      0      3      0     93      T
05      2      0      3     91      T
06     24     24     24     24      n
07     88      2      2      4      A
08     12      7     68      9      G
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12     24     24     24     24      n
13      7     68      9     12      C
14      4      2      2     88      T
15     24     24     24     24      n
16     71     12      4      9      A
17     94      0      2      0      A
18      4      2      2     88      T
19      0     96      0      0      C
20      1      2     93      0      G
Binding TFs: 5hlh_F / 5hlh_H (MarR family, HxlR-like helix-turn-helix, Sugar-specific transcriptional regulator TrmB, Transcriptional regulator PadR-like family, FeoC like transcriptional regulator, MarR family, Winged helix DNA-binding domain)
Binding Sites: 5hlh_M / 5hlh_N
			
Publications: Liu G, Liu X, Xu H, Liu X, Zhou H, Huang Z, Gan J, Chen H, Lan L, Yang CG. Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J Am Chem Soc 139:1598-1608 (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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