Transcription Factor
| Accessions: | GABPA (HT-SELEX2 May2017) |
| Names: | ENSG00000154727, GABPA |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: ETS experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: ETS experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2 |
| Length: | 274 |
| Pfam Domains: | 20-99 Sterile alpha motif (SAM)/Pointed domain 168-250 Ets-domain |
| Sequence: (in bold interface residues) | 1 ITTISDETSEQVTRWAAALEGYRKEQERLGIPYDPIQWSTDQVLHWVVWVMKEFSMTDID 60 61 LTTLNISGRELCSLNQEDFFQRVPRGEILWSHLELLRKYVLASQEQQMNEIVTVDQPVQI 120 121 IPASVQSATPTTIKVINSSAKAAKVQRAPRISGEDRSSPGNRTGNNGQIQLWQFLLELLT 180 181 DKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQ 240 241 GKRFVYKFVCDLKTLIGYSAAELNRLVTECEQKK |
| Interface Residues: | 166, 221, 222, 224, 225, 226, 228, 229, 243 |
| 3D-footprint Homologues: | 3zp5_A, 7jsa_J, 3jtg_A, 1dux_F, 8ee9_F, 4mhg_A, 8smh_F, 4uno_A, 2stt_A, 8smj_F, 4lg0_B, 1yo5_C, 4iri_A, 1awc_A, 4l18_B, 1bc8_C |
| Binding Motifs: | GABPA_2 rrCCGGAAGyr GABPA_methyl_1 rACCGGAARtr |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.