Transcription Factor

						

			
Accessions: Q4H348 (JASPAR 2024)

			
Names: Q4H348_CIOIN
Organisms: Ciona intestinalis
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q4H348
Length: 1200
Pfam Domains:    26-215 Rel homology domain (RHD)
  833-924 Ankyrin repeats (3 copies)
  870-899 Ankyrin repeat
 906-1002 Ankyrin repeats (3 copies)
 994-1056 Ankyrin repeats (3 copies)
1009-1036 Ankyrin repeat
1009-1037 Ankyrin repeat
1096-1168 Death domain
Sequence: 
(in bold interface residues)		   1 MSDQSLVLHQSTRENMFPEENGEPYLEIIENPKSRGFRFRYTCEGPSHGGIPGGSSDKNK   60
  61 KTFPAVKICNYQGYARIVVQLVTNEENPRLHPHSLVGKQCQNGICTVQCGPKDMTATFPN  120
 121 LGIQHVTKKNVATILEERYIAAEMQLSSINDGFPQEVQRNIKDEDRKRIAAKAQSEAKSI  180
 181 DLSVVRLMFIAYLPDSNGAFTIMLKPVISDAIFDSKAPNAATLKICRMDCNAGSASGGDE  240
 241 VYLLCDKVQKDDIQVVFSEEDMQGNNLWEAYGSFSPTDVHRQFAIVFRTPAYKDTEIKMP  300
 301 VNVQVQLRRKSDNEVSESRPFTYLPNKSDLELIDRKRRKVMPDFLDHTGNGSTGGYSFNP  360
 361 QAAILPSSYNFSGNTGSGNTAGNGAGKVKEARRPPQKQQNPQKGPVDPSVLMMLNRIKTE  420
 421 PKSPSPPTTYSNFPPIAYMSPAKSEPSPPAPMSIGGSPAAQVPQEEEYLPGTRIPLPKNA  480
 481 RPHTGLPQMSFQNPIVLSQQQQMQQQQIQQQQQQHLQQIQQQQAYSNYSPMYSTTYGLDN  540
 541 TQHMVYSTPSPDYGQQIIQQLSPQEVQEYEETVMNELSTVDAGDLVDIMNVDLNHNPMPQ  600
 601 TTNSNIINQAYDQANILTQTNNTYGGGSGSFRGSVVDPIIPQPLSNAPLPILSQQFSQQL  660
 661 LELTEYDLADIESDAGAERKPKPGNNNDDEQEEDYASAYCEEQDTTDSTAHEAEPKSFST  720
 721 VQSDCCNVEADAAMLKMEKLSLAPSMPTKLDSLKPEKKFDSKQVETKTKGPLKRSVTSTT  780
 781 ASVTQALEKYAVKTMNRNSSALHDFSVTGDIRMLLVLQRHLTDVRDCNGDSVLHVAVIHD  840
 841 QMQVLSSLLDVIVTLNNKQNIIDAVNPQKQTALQMAVLSDNVDAVIDLLKVGADPLVLDS  900
 901 YGNHSIHVACRHGNADILNRLLNCKQVYDMEMDTKNFDGLGCFHLAGKASSGTRQCLGLL  960
 961 REFAFDVNMPDMKSRRTALHMAVEADNIVVAGCLISECDADLEASTYEGYTPLHVAASLD 1020
1021 HCEIATLLLACGADPEASSAPPGREDGMTPLDLATSDQMRDLLNGVFMKNIKEELDNSNY 1080
1081 SDEEDLATLDPLIRLKLCKLLNLEKSGSDWYALASRLSLDYIVPFIDTTENPTDLLLDNY 1140
1141 MFKHGTVAGLRSALMNIGRHDAVQLLNRAATTTCVDKFDSNATEQCDSAFGSLPNQIDVI 1200
Interface Residues: 38, 40, 41, 43, 44, 46, 47, 48, 216, 218, 247, 281, 308, 309, 950, 951, 974, 985, 1080, 1092, 1093, 1096
3D-footprint Homologues: 2o61_A, 9bdw_A, 1imh_C, 7cli_B, 1nfk_A, 1a3q_A, 1gji_A, 1p7h_L, 8ipp_B, 8jpx_A
Binding Motifs: MA1902.1 vmaaarGGGGAATcCCCctwyy
MA1902.2 GGGGAATcCCC
			
Publications: Arizza V, Bonura A, La Paglia L, Urso A, Pinsino A, Vizzini A. Transcriptional and in silico analyses of MIF cytokine and TLR signalling interplay in the LPS inflammatory response of Ciona robusta. Sci Rep 10:11339 (2020). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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