Transcription Factor

Accessions: 5yi2_A (3D-footprint 20231221), 5yi2_E (3D-footprint 20231221)
Names: Q9CDU5_LACLA, Zinc transport transcriptional regulator
Organisms: Lactococcus lactis, Lactococcus lactis subsp. lactis (strain IL1403)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 146
Pfam Domains: 36-91 MarR family
36-93 MarR family
37-82 Winged helix-turn-helix DNA-binding
37-100 Winged helix DNA-binding domain
42-85 Transcriptional regulator
42-83 Bacterial regulatory protein, arsR family
43-115 TFIIE alpha subunit
43-82 Iron dependent repressor, N-terminal DNA binding domain
(in bold interface residues)
Interface Residues: 37, 39, 54, 64, 65, 66, 67, 69, 70, 71, 74, 91
3D-footprint Homologues: 4kdp_B, 7el3_B, 5yi2_J, 6c2s_C, 1z9c_A, 6jbx_A, 3q5f_A, 5hlg_E, 3zpl_B, 8c7s_A, 4aik_A
Binding Motifs: 5yi2_AB TTaAAnAGTTAAA
Publications: Zhu R, Song Y, Liu H, Yang Y, Wang S, Yi C, Chen PR. Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation. Proc Natl Acad Sci U S A 114:13661-13666 (2017). [Pubmed]
Related annotations: PaperBLAST

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