Transcription Factor

Accessions: 4l0z_B (3D-footprint 20231221)
Names: ETS1_HUMAN, p54, Protein C-ets-1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P14921
Length: 101
Pfam Domains: 4-85 Ets-domain
Sequence:
(in bold interface residues)
1 SGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSR 60
61 GLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAM
Interface Residues: 1, 34, 38, 39, 42, 56, 57, 59, 60, 61, 63, 64, 78
3D-footprint Homologues: 3zp5_A, 2wbs_A, 8ee9_F, 4mhg_A, 1dux_F, 4uno_A, 3jtg_A, 7jsa_J, 2stt_A, 4bqa_A, 1bc8_C, 4iri_A, 4l18_B, 1yo5_C, 1awc_A, 4lg0_B
Binding Motifs: 4l0z_AB AAgCCACATCCT
4l0z_B aGGA
Binding Sites: 4l0z_C
4l0z_D
Publications: Shrivastava T, Mino K, Babayeva N.D, Baranovskaya O.I, Rizzino A, Tahirov T.H. Structural basis of Ets1 activation by Runx1. Leukemia 28:2040-8 (2014). [Pubmed]
Related annotations: PaperBLAST

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