Transcription Factor
| Accessions: | UP00338A (UniPROBE 20160601) |
| Names: | Stp2, YHR006W, Zinc finger protein STP2 |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P38704 |
| Description: | Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes |
| Length: | 541 |
| Pfam Domains: | 204-226 Zinc finger, C2H2 type 204-226 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MPILSLSSTRNSVLTRIYDYLKALVQQVIVPNVEDDKSSKSTPFEKLEPAKQNHPQKDCC 60 61 ATEKDDLVDVSELFPKQNNKQLSLTSKSSVVPCALNLDNLGTPFSIKIDNNGAVTTQLNL 120 121 DEPILRGPSRGEPAKLQNDLISSPPLEESYINNDQYKALFPSNFLPITPVSSVITPASKK 180 181 SIDESPLSDEVQGIADESSETLPYICHYCDARFRIRGYLTRHIKKHAKRKAYHCPFFDNS 240 241 ISQELRCHTSGGFSRRDTYKTHLKSRHFTYPEGVKPQDRNKSPGVCTQCGEHFSTSESWV 300 301 ENHIEAGSCKGLPEGYSEGIREKKKTSKMKMIKTSDGQTRFISSDESVSEPALQNKNCIE 360 361 ATVMQSKERPNDKIIPTKTEKNDFGIGTQWFERKQISRPTQTTQSRGPTEVQNLKEWSII 420 421 SPPILSPQNASSVPQEYQSSRYTLHMDSPALSSASSALSPLSGDPITTTETNKSYPLDSE 480 481 QSLLEPDKTEEDAINQSKESNMISINEMLQKQMDFELLGENHLKETQDYLALYKKAYGIE 540 541 F |
| Interface Residues: | 183, 185, 186, 189, 214, 215, 216, 217, 218, 220, 221, 222, 223, 224, 227, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 266, 294, 295, 296, 297, 334, 335, 336, 337, 340 |
| 3D-footprint Homologues: | 6ml4_A, 7ysf_A, 3uk3_C, 7n5w_A, 2kmk_A, 4x9j_A, 1ubd_C, 2wbs_A, 1llm_D, 5ei9_F, 6blw_A, 1mey_C, 5k5i_A, 1f2i_J, 6e94_A, 1tf6_A, 7txc_E, 5kkq_D, 1g2f_F, 7eyi_G, 8h9h_G, 4m9v_C, 2i13_A, 2jpa_A, 7w1m_H, 5yel_A, 8ssq_A |
| Binding Motifs: | UP00338A_1 yrawygGyGCCGyrysackh |
| Binding Sites: | AACGGCGC ACGCCGCA ACGGCGCA ACGGCGCG ACGGCGCT CACGGCAC CACGGCGC CGCCGCAC CGCCGTAC CGCCGTGC GCCGCGGC GCGCCGCA GCGCCGTA GCGGCGCC GTGCCGCA GTGCCGTA AACGCCGT ACGGCGCC ATACGGCA CGCGGCGC |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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