Transcription Factor

						

			
Accessions: 2nny_A (3D-footprint 20231221), 2nny_B (3D-footprint 20231221)

			
Names: C-ets-1 protein, ETS1_HUMAN, p54, Protein C-ets-1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P14921
Length: 129
Pfam Domains:    28-109 Ets-domain
Sequence: 
(in bold interface residues)		   1 VRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSSQSFISWTGDGWEFKLSD   60
  61 PDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVSDLQSLLGYTPE  120
 121 ELHAMLDVK
Interface Residues: 25, 58, 62, 63, 66, 80, 81, 83, 84, 85, 87, 88, 102
3D-footprint Homologues: 3zp5_A, 2wbs_A, 7jsa_J, 2stt_A, 8ee9_F, 4mhg_A, 1dux_F, 4uno_A, 3jtg_A, 4l18_B, 1yo5_C, 1awc_A, 4lg0_B, 4bqa_A, 1bc8_C, 4iri_A
Binding Motifs: 2nny_AB AGGAAGnnCTTCCT
2nny_B CTTCCT
Binding Sites: 2nny_C
2nny_D
			
Publications: Lamber E.P, Vanhille L, Textor L.C, Kachalova G.S, Sieweke M.H, Wilmanns M. Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization. The EMBO journal 27:2006-17 (2008). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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