DNA Binding Motif

						

			
Accessions: 2nny_AB (3D-footprint 20231221)

			
Names: C-ets-1 protein
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the Ets1 dimer DNA complex.
Length: 14
Consensus: AGGAAGnnCTTCCT
Weblogo: 
PSSM: P0      A      C      G      T
01     88      4      0      4      A
02      0      0     96      0      G
03      0      0     96      0      G
04     96      0      0      0      A
05     72     11      4      9      A
06      9      4     76      7      G
07     24     24     24     24      n
08     24     24     24     24      n
09      4     72     11      9      C
10      4      4      4     84      T
11      0      0      0     96      T
12      0     96      0      0      C
13      0     96      0      0      C
14      0      4      4     88      T
Binding TFs: 2nny_A / 2nny_B (Ets-domain)
Binding Sites: 2nny_C
2nny_D
			
Publications: Lamber E.P, Vanhille L, Textor L.C, Kachalova G.S, Sieweke M.H, Wilmanns M. Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization. The EMBO journal 27:2006-17 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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