Transcription Factor
| Accessions: | UP00278A (UniPROBE 20160601) |
| Names: | CBF3, CBF3B, Centromere DNA-binding protein complex CBF3 subunit B, Centromere protein 3, Cep3, CSL1, YM8520.17C, YMR168C |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P40969 |
| Description: | Essential kinetochore protein, component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and ... |
| Length: | 100 |
| Pfam Domains: | 11-44 Fungal Zn(2)-Cys(6) binuclear cluster domain |
| Sequence: (in bold interface residues) | 1 FNRTTQLKSKHPCSVCTRRKVKCDRMIPCGNCRKRGQDSECMKSTKLITASSSKEYLPDL 60 61 LLFWQNYEYWITNIGLYKTKQRDLTRTPANLDTDTEECMF |
| Interface Residues: | 19, 20, 21, 46, 48, 49, 76 |
| 3D-footprint Homologues: | 1pyi_A, 6o19_A, 1hwt_C, 1zme_D, 7uik_T, 3coq_A, 6gys_C, 1orn_A |
| Binding Motifs: | UP00278A_1 ggysacyTCSGAAaymtgrg |
| Binding Sites: | ACTCGGAA ATTCCGAG ATTTCCGA CCTCGGAA CCTCGGCA CGGAAAAA CTCGGAAA CTCGGAAC CTTCGGAA GCTCGGAA GTCGGAAA GTTCCGAA GTTCGGAA GTTTCCGA TCGGAAAA TCTCGGAA TTCCCGAA TTCCGAAA TTCGGAAA CTCGGAAG |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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