Transcription Factor

Accessions: 5d5v_B (3D-footprint 20231221)
Names: Heat shock factor protein 1, Heat shock transcription factor 1, HSF 1, HSF1_HUMAN, HSTF 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q00613
Length: 96
Pfam Domains: 4-95 HSF-type DNA-binding
(in bold interface residues)
Interface Residues: 49, 50, 55, 57, 58, 59, 61, 62, 93
3D-footprint Homologues: 5hdn_C, 5d5v_B, 5d5w_B, 3hts_B, 4bqa_A, 7dci_A
Binding Motifs: 5d5v_B CnTTCCA
Binding Sites: 5d5v_A
Publications: Neudegger T, Verghese J, Hayer-Hartl M, Hartl FU, Bracher A. Structure of human heat-shock transcription factor 1 in complex with DNA. Nat Struct Mol Biol 23:140-6 (2016). [Pubmed]
Related annotations: PaperBLAST

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