Transcription Factor

Accessions: 6ycq_B (3D-footprint 20231221)
Names: ARFA_ARATH, Auxin response factor 1
Organisms: Arabidopsis thaliana
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q8L7G0
Length: 343
Pfam Domains: 112-213 B3 DNA binding domain
238-320 Auxin response factor
Sequence:
(in bold interface residues)
1 GVLSDALCRELWHACAGPLVTLPREGERVYYFPEGHMEQLEASMHQGLEQQMPSFNLPSK 60
61 ILCKVINIQRRAEPETDEVYAQITLLPELDQSEPTSPDAPVQEPEKCTVHSFCKTLTASD 120
121 TSTHGGFSVLRRHADDCLPPLDMSQQPPWQELVATDLHNSEWHFRHIFRGQPRRHLLTTG 180
181 WSVFVSSKKLVAGDAFIFLRGENEELRVGVRRHMRQQTNIPSSVISSHSMHIGVLATAAH 240
241 AITTGTIFSVFYKPRTSRSEFIVSVNRYLEAKTQKLSVGMRFKMRFEGEEAPEKRFSGTI 300
301 VGVQENKSSVWHDSEWRSLKVQWDEPSSVFRPERVSPWELEPL
Interface Residues: 119, 124, 125, 126, 128, 169, 171, 172, 174
3D-footprint Homologues: 7et6_A, 6sdg_B, 6ycq_A
Binding Motifs: 6ycq_AB TGTCGGtnnnnnGCCGACAA
Binding Sites: 6ycq_C
6ycq_D
Publications: Freire-Rios A, Tanaka K, Crespo I, van der Wijk E, Sizentsova Y, Levitsky V, Lindhoud S, Fontana M, Hohlbein J, Boer DR, Mironova V, Weijers D. Architecture of DNA elements mediating ARF transcription factor binding and auxin-responsive gene expression in Arabidopsis. Proc Natl Acad Sci U S A 117:24557-24566 (2020). [Pubmed]
Related annotations: PaperBLAST

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