Transcription Factor

						

			
Accessions: 6ide_B (3D-footprint 20231221)

			
Names: A0A655PXP1_VIBCL, Transcriptional regulator LuxR family
Organisms: Vibrio cholerae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: A0A0H6
Length: 228
Pfam Domains:    12-123 PAS fold
  147-202 Bacterial regulatory proteins, luxR family
Sequence: 
(in bold interface residues)		   1 PNHLTLEQISLFKQLPGYWGCKDLNSVFVYANQAYGELIGLKRAEDCIGRTDFEMPSPTA   60
  61 ACAAEFQQQDRYVIETGHSVKVLDIHPYPDGHWHAHIFTKTPWRDSQGKIQGTIFFGQDL  120
 121 TDTAILEVGHWVCRATGLSTSTTFTLKLTARESEVLFLLLYGKKPQHIARVMGISIKTVE  180
 181 GYEAKLRSKFGALSKDQLIDLALDRGFGSVIPKTLLRKQLSVVLSDHT
Interface Residues: 88, 89, 96, 98, 106, 108, 110, 175, 176, 177, 178, 180, 181, 182, 184
3D-footprint Homologues: 7et4_D, 7ve5_B, 5w43_B, 6ide_A, 1zlk_A, 4wuh_B, 8dq1_C
Binding Motifs: 6ide_AB GGGgnnnncCcC
Binding Sites: 6ide_C
6ide_D
			
Publications: Wu H, Li M, Guo H, Zhou H, Li B, Xu Q, Xu C, Yu F, He J. Crystal structure of the Vibrio cholerae VqmA-ligand-DNA complex provides insight into ligand-binding mechanisms relevant for drug design. J Biol Chem 294:2580-2592 (2019). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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