Transcription Factor
Accessions: | 3oqo_A (3D-footprint 20231221) |
Names: | Catabolite control protein A, CCPA_BACSU, Glucose-resistance amylase regulator |
Organisms: | Bacillus subtilis, strain 168 |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P25144 |
Length: | 333 |
Pfam Domains: | 4-49 Bacterial regulatory proteins, lacI family 61-272 Periplasmic binding proteins and sugar binding domain of LacI family 63-312 Periplasmic binding protein domain 171-331 Periplasmic binding protein-like domain |
Sequence: (in bold interface residues) | 1 MNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 60 61 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 120 121 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI 180 181 AFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKP 240 241 TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAV 300 301 AMRLLTKLMNKEPVEEHIVELPHRIELRKSTKA |
Interface Residues: | 5, 6, 15, 16, 17, 18, 20, 21, 27, 28, 29, 52, 55, 56 |
3D-footprint Homologues: | 1efa_B, 3oqm_C, 7ce1_D, 1l1m_B, 1zvv_A, 1jft_A |
Binding Motifs: | 3oqo_AC TGnraACGcnnaCA |
Publications: | Schumacher M.A, Sprehe M, Bartholomae M, Hillen W, Brennan R.G. Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators. Nucleic acids research 39:2931-42 (2011). [Pubmed] |
Related annotations: | PaperBLAST |
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