Transcription Factor

Accessions: 3oqo_A (3D-footprint 20231221)
Names: Catabolite control protein A, CCPA_BACSU, Glucose-resistance amylase regulator
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P25144
Length: 333
Pfam Domains: 4-49 Bacterial regulatory proteins, lacI family
61-272 Periplasmic binding proteins and sugar binding domain of LacI family
63-312 Periplasmic binding protein domain
171-331 Periplasmic binding protein-like domain
Sequence:
(in bold interface residues)
1 MNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 60
61 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 120
121 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI 180
181 AFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKP 240
241 TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAV 300
301 AMRLLTKLMNKEPVEEHIVELPHRIELRKSTKA
Interface Residues: 5, 6, 15, 16, 17, 18, 20, 21, 27, 28, 29, 52, 55, 56
3D-footprint Homologues: 7ce1_D, 1efa_B, 3oqm_C, 1l1m_B, 1jft_A, 1zvv_A
Binding Motifs: 3oqo_AC TGnraACGcnnaCA
Publications: Schumacher M.A, Sprehe M, Bartholomae M, Hillen W, Brennan R.G. Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators. Nucleic acids research 39:2931-42 (2011). [Pubmed]
Related annotations: PaperBLAST

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