Transcription Factor
| Accessions: | UP00519A (UniPROBE 20160601) |
| Names: | D.mel FoxN1/4, DOMINA protein, Jumeau, Winged-helix nude transcription factor, Winged-helix protein |
| Organisms: | Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Length: | 719 |
| Pfam Domains: | 411-502 Fork head domain |
| Sequence: (in bold interface residues) | 1 MFELEDYSSGIHEGFFSKYADAAGPSLDFYVSDSMQEMLNVDIRAEIANVVGSSSSDLTS 60 61 SLDQTLEAISAINNNQSNGNSSQSASYNANANFLTSSGLHASPTAKWMGSSANFWSNSDY 120 121 YADLGACVNPISVMPLINSTSAGMFSPKKNKTASSTQGRSGAVPSSPSAERDQHKSHLTF 180 181 SPAQMKVSAGSMRRDQVMAHIPKQISVVTGTGTTAPATMATNSVLQRRNSSAVDAVRKDL 240 241 VTELRKAQSSPVPNSLEELGKGKGSTLLNASVGATNTIKLAPGIGGLTFANSAAYQKLKQ 300 301 TSLVKSPGGISPGAGSNMGLKREDSNKRGLQASTTPKSIASAANSPHHQMQSNYSLGSPS 360 361 SLSSSSASSPLGNVSNLVNIANNNTSGAGSGLVKPLQQKVKLPPVGSPFPKPAYSYSCLI 420 421 ALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWKNSVRHNLSLNKCFEKIERPATNGN 480 481 QRKGCRWAMNPDRINKMDEEVQKWSRKDPAAIRGAMVYPQHLESLERGEMKHGSADSDVE 540 541 LDSQSEIEESSDLEEHEFEDTMVDAMLVEEEDEEEDGDDDEQIINDFDAEDERHANGNQA 600 601 NNLPINHPLLGQKSNDFDIEVGDLYDAIDIEDDKESVRRIISNDQHIIELNPADLNATDG 660 661 YNQQPALKRARVDINYAIGPAGELEQQYGQKVKVQQVIQPQQHPPTYNRRKMPLVNRVI |
| Interface Residues: | 451, 454, 456, 457, 458, 460, 461, 462, 464, 465, 476, 483 |
| 3D-footprint Homologues: | 3l2c_A, 7vox_H, 2hdc_A, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 3qrf_G |
| Binding Motifs: | UP00519A_1 agmwywragyGACGCgbmvtya UP00519A_2 tskgytvATgGCGTCykgamwy |
| Binding Sites: | ACGCGTCA ACGCGTCG GACGCGTA AAGCGTCA ATCGCGTC ATGACGCC ATGACGCG ATGGCGTC CCGACGCG CGACGCGC CGACGCTA CGCGTCGC GACGCCGC GACGCTAC GCGACGCC GCGTCATA GGCGTCAC TAGCGTCA TCGCGTCA TGACGCCA |
| Publications: | Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.