DNA Binding Motif

Accessions: UP00519A_1 (UniPROBE 20160601)
Names: D.mel FoxN1/4, DOMINA protein, Jumeau, Winged-helix nude transcription factor, Winged-helix protein
Organisms: Drosophila melanogaster
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 22
Consensus: agmwywragyGACGCgbmvtya
Weblogo:
PSSM: P0 A C G T
01 0.52 0.16 0.09 0.24 a
02 0.22 0.16 0.43 0.19 g
03 0.43 0.26 0.21 0.10 m
04 0.58 0.04 0.13 0.25 w
05 0.21 0.28 0.13 0.38 y
06 0.38 0.19 0.14 0.30 w
07 0.56 0.09 0.29 0.06 r
08 0.59 0.13 0.08 0.19 a
09 0.22 0.08 0.52 0.18 g
10 0.11 0.37 0.10 0.42 y
11 0.04 0.03 0.92 0.02 G
12 0.94 0.01 0.02 0.03 A
13 0.04 0.94 0 0.01 C
14 0.01 0 0.96 0.02 G
15 0.01 0.98 0 0.01 C
16 0.03 0.22 0.59 0.15 g
17 0.21 0.28 0.25 0.26 b
18 0.37 0.40 0.11 0.12 m
19 0.29 0.28 0.27 0.16 v
20 0.18 0.17 0.15 0.50 t
21 0.23 0.33 0.11 0.33 y
22 0.66 0.10 0.13 0.11 a
Binding TFs: UP00519A (Fork head domain)
Binding Sites: ACGCGTCA
ACGCGTCG
GACGCGTA
AAGCGTCA
ATCGCGTC
ATGACGCC
ATGACGCG
ATGGCGTC
CCGACGCG
CGACGCGC
CGACGCTA
CGCGTCGC
GACGCCGC
GACGCTAC
GCGACGCC
GCGTCATA
GGCGTCAC
TAGCGTCA
TCGCGTCA
TGACGCCA
Publications: Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed]

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