DNA Binding Site

Accessions: 1h6f_C (3D-footprint 20231221), 1h6f_D (3D-footprint 20231221), 4a04_D (3D-footprint 20231221), 4a04_E (3D-footprint 20231221)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 22
Sequence: ATTTCACACCTAGGTGTGAAAT
Type: Heterodimer
Binding TFs: 1h6f_B (T-box)
4a04_B (T-box)
Binding Motifs: 1h6f_AB TnnnCACctAGgTGnnnA
1h6f_B gTGnnnA
4a04_AB TnnnCACcnaGgTGnnnA
Publications: Coll M, Seidman J.G, Müller C.W. Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome. Structure (London, England : 1993) 10:343-56 (2002). [Pubmed]

El Omari K, De Mesmaeker J, Karia D, Ginn H, Bhattacharya S, Mancini E.J. Structure of the DNA-bound T-box domain of human TBX1, a transcription factor associated with the DiGeorge syndrome. Proteins : (2011). [Pubmed]

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