Transcription Factor
Accessions: | 1h6f_B (3D-footprint 20231221) |
Names: | T-box protein 3, T-BOX TRANSCRIPTION FACTOR TBX3, TBX3_HUMAN |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | O15119 |
Length: | 186 |
Pfam Domains: | 5-186 T-box |
Sequence: (in bold interface residues) | 1 KDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAAD 60 61 DCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGF 120 121 TILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPF 180 181 AKGFRD |
Interface Residues: | 31, 163, 164, 180, 183, 184 |
3D-footprint Homologues: | 6f59_B, 2x6v_A, 4a04_B, 1h6f_B, 5flv_I, 1xbr_B |
Binding Motifs: | 1h6f_AB TnnnCACctAGgTGnnnA 1h6f_B gTGnnnA |
Binding Sites: | 1h6f_C / 1h6f_D |
Publications: | Coll M, Seidman J.G, Müller C.W. Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome. Structure (London, England : 1993) 10:343-56 (2002). [Pubmed] |
Related annotations: | PaperBLAST |
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