Transcription Factor

						

			
Accessions: 1h6f_B (3D-footprint 20231221)

			
Names: T-box protein 3, T-BOX TRANSCRIPTION FACTOR TBX3, TBX3_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: O15119
Length: 186
Pfam Domains:     5-186 T-box
Sequence: 
(in bold interface residues)		   1 KDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAAD   60
  61 DCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGF  120
 121 TILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPF  180
 181 AKGFRD
Interface Residues: 31, 163, 164, 180, 183, 184
3D-footprint Homologues: 5flv_I, 1xbr_B, 6f59_B, 2x6v_A, 4a04_B, 1h6f_B
Binding Motifs: 1h6f_AB TnnnCACctAGgTGnnnA
1h6f_B gTGnnnA
Binding Sites: 1h6f_C / 1h6f_D
			
Publications: Coll M, Seidman J.G, Müller C.W. Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome. Structure (London, England : 1993) 10:343-56 (2002). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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