DNA Binding Site

Accessions: 2f8x_Y (3D-footprint 20231221), 3v79_Y (3D-footprint 20231221)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 18
Sequence: TTTCTTTCCCACAGTAAC
Binding TFs: 2f8x_C / 3v79_C (IPT/TIG domain, Beta-trefoil DNA-binding domain, LAG1, DNA binding)
Binding Motifs: 2f8x_C TTCCCACA
3v79_C TGTGGGAA
Publications: Nam Y, Sliz P, Song L, Aster J.C, Blacklow S.C. Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Cell 124:973-83 (2006). [Pubmed]

Choi S.H, Wales T.E, Nam Y, O'Donovan D.J, Sliz P, Engen J.R, Blacklow S.C. Conformational locking upon cooperative assembly of notch transcription complexes. Structure (London, England : 1993) 20:340-9 (2012). [Pubmed]

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