DNA Binding Motif

						

			
Accessions: ETV7_1 (HumanTF2 1.0), MA1708.1 (JASPAR 2024)

			
Names: ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: HT-SELEX; HT-SELEX generated reference PWM, HT-SELEX
Length: 11
Consensus: rgscGGAARTr
Weblogo: 
PSSM: P0      A      C      G      T
01   2762    569   2081   1424      r
02   1408   1227   2823   1379      g
03   2249   4187   6836    800      s
04   1878   6836    919    923      c
05      0      4   6836      0      G
06      2      4   6836     20      G
07   6836      0      0     35      A
08   6836     58      3    118      A
09   3070     89   6836      0      R
10    390    665    962   6836      T
11   3564    721   6836   1162      r
Type: Heterodimer
Binding TFs: Q9Y603 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
Q9Y603
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]


Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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