DNA Binding Motif

						

			
Accessions: ETV2_HES7_2_3 (HumanTF2 1.0)

			
Names: ETV2_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: rsCGGAwrygrhggCrCGyGsc
Weblogo: 
PSSM: P0      A      C      G      T
01   2283    565   1609    719      r
02    842   2611   1281    293      s
03    770   3892     17      6      C
04      0     17   3892      0      G
05     13      0   3892      4      G
06   3892     10     28     66      A
07   3892    119      0   1805      w
08   1318    345   2191     37      r
09    274   1484    378   1756      y
10    635    651   2038    567      g
11   1275    830   1024    763      r
12    979   1036    888    988      h
13    913    516   2004    459      g
14    863    878   1814    337      g
15     63   3892      0     21      C
16   3892     42   2678    436      r
17     11   3892      0     15      C
18     26     20   3892     33      G
19    247   1757     95   3892      y
20     30     13   3892     52      G
21    197   1746   1087    862      s
22    446   1846    687    912      c
Type: Heterodimer
Binding TFs: HES7_TF2 (Helix-loop-helix DNA-binding domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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