DNA Binding Motif

						

			
Accessions: 2puc_A (3D-footprint 20231221)

			
Names: PROTEIN (PURINE REPRESSOR)
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
Length: 8
Consensus: CGcanACg
Weblogo: 
PSSM: P0      A      C      G      T
01      0     96      0      0      C
02      0      0     96      0      G
03     12     60     12     12      c
04     31     21     21     23      a
05     24     24     24     24      n
06     96      0      0      0      A
07      4     81      7      4      C
08     16     19     45     16      g
Binding TFs: 2puc_A (Bacterial regulatory proteins, lacI family, Periplasmic binding proteins and sugar binding domain of LacI family, Periplasmic binding protein-like domain, Periplasmic binding protein domain)
Binding Sites: 2puc_B
			
Publications: Schumacher M.A, Choi K.Y, Zalkin H, Brennan R.G. Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. Science (New York, N.Y.) 266:763-70 (1994). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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