DNA Binding Motif

Accessions: 2d5v_B (3D-footprint 20231221)
Names: Hepatocyte nuclear factor 6
Organisms: Rattus norvegicus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of HNF-6alpha DNA-binding domain in complex with the TTR promoter
Length: 9
Consensus: TgGTCAaTA
Weblogo:
PSSM: P0 A C G T
01 8 8 8 72 T
02 16 8 56 16 g
03 0 0 96 0 G
04 0 0 0 96 T
05 0 96 0 0 C
06 96 0 0 0 A
07 64 16 8 8 a
08 0 0 0 96 T
09 96 0 0 0 A
Binding TFs: 2d5v_B (Homeobox domain, CUT domain)
Binding Sites: 2d5v_E
2d5v_F
Publications: Iyaguchi D, Yao M, Watanabe N, Nishihira J, Tanaka I. DNA recognition mechanism of the ONECUT homeodomain of transcription factor HNF-6. Structure (London, England : 1993) 15:75-83 (2007). [Pubmed]

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