Transcription Factor

						

			
Accessions: 2d5v_B (3D-footprint 20231221)

			
Names: Hepatocyte nuclear factor 6, HNF-6, HNF6_RAT, One cut domain family member 1, One cut homeobox 1
Organisms: Rattus norvegicus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: A4II00
Length: 135
Pfam Domains:      2-77 CUT domain
   80-131 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFR   60
  61 RMWKWLQEPEFQRMSALRLPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELST  120
 121 VSNFFMNARRRSLDK
Interface Residues: 28, 29, 30, 33, 34, 35, 36, 37, 38, 40, 41, 44, 48, 58, 61, 73, 81, 122, 123, 126, 127, 130, 131
3D-footprint Homologues: 1au7_A, 2o4a_A, 2d5v_B, 6y93_B, 1e3o_C, 2hos_A, 5hod_A, 4qtr_D, 6fqq_E, 4xrm_B, 1o4x_A, 1puf_B, 8g87_X, 3l1p_A, 6fqp_B
Binding Motifs: 2d5v_B TgGTCAaTA
Binding Sites: 2d5v_E
2d5v_F
			
Publications: Iyaguchi D, Yao M, Watanabe N, Nishihira J, Tanaka I. DNA recognition mechanism of the ONECUT homeodomain of transcription factor HNF-6. Structure (London, England : 1993) 15:75-83 (2007). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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