DNA Binding Motif

						

			
Accessions: GCM1_FIGLA_2_3_4_5_6 (HumanTF2 1.0)

			
Names: GCM1_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: CAssTGkaamtaCCmgCAy
Weblogo: 
PSSM: P0      A      C      G      T
01     16    928      0      4      C
02    928      6      0      0      A
03     14   1633    928     25      s
04     12    928   1295     13      s
05     12      1      2    928      T
06     30     16    928      0      G
07     79    183    264    402      k
08    355    211    176    186      a
09    510    188    189     42      a
10    267    501     50    110      m
11    211    217    117    383      t
12    559    138    200     31      a
13     23    928      1      0      C
14     17    928      0      0      C
15    494    928     30    194      m
16    288     65    928    352      g
17      0    928      6    138      C
18    928     36     43     38      A
19     50    421    140    507      y
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
GCM1_TF1 (GCM motif protein)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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