DNA Binding Motif

Accessions: 4fx4_AB (3D-footprint 20231221)
Names: PROBABLE TRANSCRIPTIONAL REPRESSOR PROTEIN
Organisms: Mycobacterium tuberculosis, strain CDC 1551 / Oshkosh
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of M. tuberculosis transcriptional regulator MOSR (Rv1049) in compex with DNA
Length: 17
Consensus: ATnCGTGTannTACACG
Weblogo:
PSSM: P0 A C G T
01 69 11 11 5 A
02 7 11 5 73 T
03 24 24 24 24 n
04 0 96 0 0 C
05 0 0 96 0 G
06 0 0 0 96 T
07 0 0 96 0 G
08 0 0 0 96 T
09 62 11 16 7 a
10 24 24 24 24 n
11 24 24 24 24 n
12 5 5 11 75 T
13 91 5 0 0 A
14 0 96 0 0 C
15 96 0 0 0 A
16 0 96 0 0 C
17 0 0 96 0 G
Binding TFs: 4fx4_A (MarR family, Transcriptional regulator, MarR family, Winged helix DNA-binding domain)
Binding Sites: 4fx4_C
4fx4_D
Publications: Brugarolas P, Movahedzadeh F, Wang Y, Zhang N, Bartek I.L, Gao Y.N, Voskuil M.I, Franzblau S.G, He C. The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis. The Journal of biological chemistry 287:37703-12 (2012). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.