Transcription Factor

						

			
Accessions: 4fx4_A (3D-footprint 20231221)

			
Names: O53397_MYCTO, PROBABLE TRANSCRIPTIONAL REPRESSOR PROTEIN
Organisms: Mycobacterium tuberculosis, strain CDC 1551 / Oshkosh
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: O53397
Length: 128
Pfam Domains:     25-80 MarR family
    27-90 Winged helix DNA-binding domain
    27-77 MarR family
    32-80 Transcriptional regulator
Sequence: 
(in bold interface residues)		   1 ECACYTTRRAARQLGQAYDRALRPSGLTNTQFSTLAVISLSEGSDLTMSELAARIGVERT   60
  61 TLTRNLEVMRRDGLVRVMAGCKRIELTAKGRAALQKAVPLWRGVQAEVTAWPRVRRDIAN  120
 121 LGQAAEAC
Interface Residues: 49, 58, 59, 60, 61, 63, 64, 65, 68, 79, 80, 81
3D-footprint Homologues: 6q2b_B, 1u8r_B, 1z9c_A, 7d98_Q, 5xxp_A, 2isz_B, 4p9u_F, 1h9t_B, 6c2s_C, 3q5f_A, 5hlg_E, 4aik_A, 4fx4_B, 5hso_A, 7obn_A
Binding Motifs: 4fx4_AB ATnCGTGTannTACACG
Binding Sites: 4fx4_C
4fx4_D
			
Publications: Brugarolas P, Movahedzadeh F, Wang Y, Zhang N, Bartek I.L, Gao Y.N, Voskuil M.I, Franzblau S.G, He C. The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis. The Journal of biological chemistry 287:37703-12 (2012). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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