DNA Binding Motif

						

			
Accessions: CUX1_SOX15_2_3 (HumanTF2 1.0)

			
Names: CUX1_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: rATCrATammcktwrawCAAwrs
Weblogo: 
PSSM: P0      A      C      G      T
01     25     13     41     14      r
02     94      0      4      2      A
03      1      1      3     94      T
04      1     94      1      9      C
05     48      0     47      0      r
06     94      0      0      5      A
07      6      4      1     94      T
08     44     21     19     11      a
09     29     30     21     14      m
10     29     31     15     19      m
11     15     35     22     22      c
12     22     11     38     24      k
13     23     23     17     30      t
14     35     17     15     27      w
15     30     10     36     19      r
16     94     32     41     23      a
17     94     10     12     53      w
18      3     94      7     20      C
19     94      4      8      7      A
20     94      3      3     11      A
21     47      7      4     94      w
22     42     12     52      4      r
23     34     45     49     15      s
Type: Heterodimer
Binding TFs: CUX1_TF1 (Homeobox domain, CUT domain, Homeobox KN domain)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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