DNA Binding Motif

						

			
Accessions: GCM1_FIGLA_2_3_4_5_6_7 (HumanTF2 1.0)

			
Names: GCM1_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: CAssTGkkcsmgrskcATGCGGG
Weblogo: 
PSSM: P0      A      C      G      T
01      2   1244      3      4      C
02   1244     21      0     49      A
03      0    910   1244      0      s
04      3   1244   1861      9      s
05     16      0      1   1244      T
06      0      0   1244      0      G
07     31     73    638    501      k
08    185     62    601    396      k
09    118    701    193    231      c
10     97    336    751     59      s
11    319    490    220    215      m
12    265    106    637    236      g
13    472    203    406    163      r
14    282    430    370    162      s
15     66    250    548    379      k
16    226    481    276    260      c
17    938     23    269     13      A
18     23     29     39   1244      T
19    148     37   1244      0      G
20     85   1244    105    118      C
21    199     25   1244    287      G
22      0      0   1244     11      G
23      0      0   1244      0      G
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
GCM1_TF1 (GCM motif protein)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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