DNA Binding Motif

						

			
Accessions: ETV2_DLX2_1 (HumanTF2 1.0)

			
Names: ETV2_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: acCGGAWrTwrmbyAATTR
Weblogo: 
PSSM: P0      A      C      G      T
01    419     51    117     71      a
02    116    537    187     68      c
03     23    537      4      4      C
04      0      0    537      0      G
05      0      0    537      0      G
06    537      0      0      0      A
07    537     20      0    206      W
08    319      9    177     32      r
09      0    109     44    385      T
10    186     73    127    151      w
11    141    123    239     33      r
12    156    199    133     49      m
13     77    188    137    134      b
14     26    213     12    324      y
15    537     86     47     57      A
16    537    126     15    101      A
17      0      0      0    537      T
18     23     18     52    537      T
19    537      2    197     47      R
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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