DNA Binding Motif

						

			
Accessions: MA1645.1 (JASPAR 2024)

			
Names: NKX2-2
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 14
Consensus: hawCCACTCAAvwa
Weblogo: 
PSSM: P0      A      C      G      T
01   6953   6959   4904   7207      h
02   9464   5638   4854   6067      a
03   7295   5558   6329   6841      w
04   2438  20232   2293   1060      C
05    618  24341    176    888      C
06  23748    463    257   1555      A
07    478  24693    420    432      C
08    490    452    295  24786      T
09    397  24058    838    730      C
10  21326   2772    580   1345      A
11  20003   2104   2266   1650      A
12   6909   6627   7589   4898      v
13   7980   5942   5554   6547      w
14   7413   6271   6050   6289      a
Type: Heterodimer
Binding TFs: O95096 (Homeobox domain)
O95096
Binding Sites: MA1645.1.1
MA1645.1.10 / MA1645.1.9
MA1645.1.11
MA1645.1.12
MA1645.1.12 / MA1645.1.13
MA1645.1.13 / MA1645.1.14
MA1645.1.14 / MA1645.1.15
MA1645.1.15 / MA1645.1.16
MA1645.1.16 / MA1645.1.17
MA1645.1.17 / MA1645.1.18
MA1645.1.19
MA1645.1.2 / MA1645.1.3
MA1645.1.18 / MA1645.1.20
MA1645.1.3
MA1645.1.4
MA1645.1.5
MA1645.1.6
MA1645.1.7
MA1645.1.7 / MA1645.1.8
MA1645.1.8 / MA1645.1.9
MA1645.1.10
MA1645.1.19
MA1645.1.2
MA1645.1.20
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.