DNA Binding Motif

						

			
Accessions: RFX3_FIGLA_1 (HumanTF2 1.0)

			
Names: RFX3_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 24
Consensus: GTTgCyatGgcracgsmmCAssTG
Weblogo: 
PSSM: P0      A      C      G      T
01     91     29   1570     40      G
02     31    126     47   1570      T
03    151    244    113   1570      T
04    487    182   1570    181      g
05     61   1570    203    375      C
06     52   1030     72    540      y
07    919    193    250    208      a
08    287    198    294    791      t
09    187     88   1214     81      G
10    203    306    994     66      g
11    309    556    366    338      c
12    743    154    464    210      r
13    782    343    174    271      a
14    201    805    257    307      c
15    359    338    699    174      g
16    257    524    473    316      s
17    456    519    256    339      m
18    426    730    320     94      m
19     29   1570      0     15      C
20   1570     24     13     68      A
21      3    555   1015      2      s
22      4    929    641      0      s
23     45      0     33   1570      T
24     48      0   1570     28      G
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
RFX3_TF1 (RFX DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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