DNA Binding Motif

Accessions: ETV5_EVX1_2_3 (HumanTF2 1.0)
Names: ETV5_EVX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: rsmGGWAATgrgyvaTtAk
Weblogo:
PSSM: P0 A C G T
01 146 65 119 51 r
02 34 97 169 27 s
03 117 265 24 3 m
04 0 0 265 0 G
05 4 0 265 7 G
06 191 0 0 74 W
07 265 0 42 25 A
08 265 4 40 7 A
09 14 52 20 265 T
10 62 40 99 64 g
11 67 18 163 18 r
12 48 59 96 62 g
13 28 87 61 89 y
14 78 82 76 30 v
15 265 38 56 99 a
16 17 0 2 265 T
17 47 62 26 265 t
18 265 15 33 75 A
19 64 35 94 72 k
Type: Heterodimer
Binding TFs: ETV5_TF1 (Ets-domain)
EVX1_TF1 / EVX1_TF2 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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