DNA Binding Motif

Accessions: 1h9d_A (3D-footprint 20231221)
Names: CORE-BINDING FACTOR ALPHA SUBUNIT1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Aml1/cbf-beta/dna complex
Length: 8
Consensus: tGCGGTtG
Weblogo:
PSSM: P0 A C G T
01 14 6 12 64 t
02 0 0 96 0 G
03 0 96 0 0 C
04 0 0 96 0 G
05 0 0 96 0 G
06 2 6 12 76 T
07 21 12 12 51 t
08 6 1 83 6 G
Binding TFs: 1h9d_A (Runt domain)
Binding Sites: 1h9d_E
1h9d_F
Publications: Bravo J, Li Z, Speck N.A, Warren A.J. The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp. Nature structural biology 8:371-8 (2001). [Pubmed]

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