DNA Binding Motif

Accessions: ETV2_TBX21_1 (HumanTF2 1.0)
Names: ETV2_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 28
Consensus: gGTGTkAaarmkrkkTvwCRCmGGAwrk
Weblogo:
PSSM: P0 A C G T
01 620 401 1817 178 g
02 10 77 2438 74 G
03 3 694 12 2438 T
04 8 0 2438 1 G
05 289 512 140 2438 T
06 189 457 1564 874 k
07 1904 145 533 177 A
08 1135 243 474 585 a
09 924 428 560 526 a
10 787 202 889 560 r
11 798 869 559 212 m
12 241 560 1021 615 k
13 747 81 1388 221 r
14 337 375 1039 686 k
15 513 415 688 821 k
16 118 299 209 1811 T
17 620 1042 727 48 v
18 1227 60 458 694 w
19 14 2438 0 23 C
20 1669 3 764 2 R
21 150 2438 223 21 C
22 1205 1233 53 0 m
23 0 0 2438 9 G
24 0 0 2438 0 G
25 2438 0 33 4 A
26 2438 554 14 1296 w
27 771 200 1667 37 r
28 186 275 691 1286 k
Type: Heterodimer
Binding TFs: TBX21_TF2 (T-box)
ETV2_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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