DNA Binding Motif

Accessions: ETV2_TBX21_2 (HumanTF2 1.0)
Names: ETV2_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: TmrCrCmGGAwry
Weblogo:
PSSM: P0 A C G T
01 691 1434 632 6273 T
02 2473 3801 1546 329 m
03 6273 372 3067 797 r
04 173 6273 255 586 C
05 6273 34 3049 87 r
06 694 6273 784 77 C
07 2491 3783 56 0 m
08 6 6 6273 0 G
09 0 3 6273 30 G
10 6273 0 25 82 A
11 6273 683 417 4137 w
12 2106 536 4168 173 r
13 756 2211 1205 2101 y
Type: Heterodimer
Binding TFs: TBX21_TF2 (T-box)
ETV2_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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