DNA Binding Motif

						

			
Accessions: ETV2_NHLH1_2 (HumanTF2 1.0)

			
Names: ETV2_NHLH1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: wcmGGAwgkramGCAGCTGCk
Weblogo: 
PSSM: P0      A      C      G      T
01   2234    241    449   1324      w
02   1933   4247   2299    974      c
03   2162   4247     57      5      m
04      3      1   4247      8      G
05      0      8   4247      0      G
06   4247    175     13     56      A
07   4247    425     15   3633      w
08    802    612   2831      2      g
09    321    374   2001   1552      k
10   1441    212   1851    744      r
11   1731    826    887    803      a
12   1371   2033    473    370      m
13    181    151   3559    357      G
14     19   4247      0     49      C
15   4247     10      0      0      A
16     27     69   4247     22      G
17     25   4247      0      0      C
18     25      0      4   4247      T
19      8      0   4247     18      G
20    169   3806    112    159      C
21     92    930   1713   1513      k
Type: Heterodimer
Binding TFs: NHLH1_TF2 (Helix-loop-helix DNA-binding domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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