DNA Binding Motif

						

			
Accessions: 5e6c_AB (3D-footprint 20231221)

			
Names: Glucocorticoid receptor
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Glucocorticoid receptor DNA binding domain - CCL2 NF-kB response element complex
Length: 8
Consensus: AAtnTCCA
Weblogo: 
PSSM: P0      A      C      G      T
01     96      0      0      0      A
02     96      0      0      0      A
03      7     16     14     59      t
04     24     24     24     24      n
05      7      7      7     75      T
06      0     81      8      7      C
07      0     96      0      0      C
08     73     14      2      7      A
Type: Heterodimer
Binding TFs: 5e6c_B (Zinc finger, C4 type (two domains))
5e6c_A (Zinc finger, C4 type (two domains))
Binding Sites: 5e6c_C
5e6c_D
			
Publications: Hudson WH, Vera IMS, Nwachukwu JC, Weikum ER, Herbst AG, Yang Q, Bain DL, Nettles KW, Kojetin DJ, Ortlund EA. Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements. Nat Commun 9:1337 (2018). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.