DNA Binding Motif

						

			
Accessions: MA0014.2 (JASPAR 2024)

			
Names: PAX5
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 19
Consensus: vwrrkCAgysraGCrtRaC
Weblogo: 
PSSM: P0      A      C      G      T
01    261    228    333     74      v
02    315     59    222    300      w
03    308     30    546     12      r
04    245    148    336    167      r
05      0    169    455    272      k
06     39    736      0    121      C
07    766     21     83     26      A
08    152    163    533     48      g
09      9    538     35    314      y
10    174    419    294      9      s
11    542      8    344      2      r
12    537     17    185    157      a
13      0    215    679      2      G
14      3    751     17    125      C
15    317     17    540     22      r
16    153     41    155    547      t
17    225      6    659      6      R
18    587     33    222     54      a
19    152    667     25     52      C
Type: Heterodimer
Binding TFs: Q02548 ('Paired box' domain, Paired-box protein 2 C terminal)
Q02548
Binding Sites: MA0014.2.1
MA0014.2.10
MA0014.2.11
MA0014.2.12
MA0014.2.13
MA0014.2.14
MA0014.2.15
MA0014.2.16
MA0014.2.17
MA0014.2.18
MA0014.2.19
MA0014.2.2
MA0014.2.20
MA0014.2.3
MA0014.2.4
MA0014.2.5
MA0014.2.6
MA0014.2.7
MA0014.2.8
MA0014.2.9
			
Publications: Czerny T., Schaffner G., Busslinger M. DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. Genes Dev. 7:2048-2061 (1993). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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