DNA Binding Motif

						

			
Accessions: ETV2_HES7_1 (HumanTF2 1.0)

			
Names: ETV2_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: ggCrCGyGsckrcCGGAwry
Weblogo: 
PSSM: P0      A      C      G      T
01    887    648   2763    781      g
02   1098   1141   2306    533      g
03    112   5079     10     41      C
04   5079    179   2178    411      r
05     11   5079     45     17      C
06     30      0   5079     19      G
07    296   2922    183   5079      y
08     58      0   5079     64      G
09    170   2102   1584   1223      s
10    950   2130   1139    860      c
11   1005    918   1830   1327      k
12   2099    391   1805    784      r
13    738   2971   1202    169      c
14    840   5079    115     36      C
15      6     12   5079     29      G
16      2     80   5079     13      G
17   5079      7     16     56      A
18   3519    273      0   1560      w
19   1591    340   3489    121      r
20    349   2228    474   2851      y
Type: Heterodimer
Binding TFs: HES7_TF2 (Helix-loop-helix DNA-binding domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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